Useful For

Sex hormone-binding globulin (SHBG) is the blood transport protein for testosterone and estrogen.

Measurement is useful in monitoring the following conditions:

• Diagnosis and follow-up of women with symptoms or signs of androgen excess.
• Monitoring sex-steroid and anti-androgen therapy.
• Aid in the diagnosis of disorders of puberty.
• Aid in the diagnosis and follow-up of anorexia nervosa.
• Aid in the follow-up of thyrotoxicosis.
• Possible adjunct in diagnosis and follow-up of insulin resistance and cardiovascular type 2 diabetes risk assessment, particularly in women.
• Crucial in the assessment of the level of free testosterone when the free testosterone is determined by calculation.                    

              Note: SHBG is included in Testosterone Total and Free (TESFT)