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HelpTest Code UTLC Immunoglobulin Total Light Chains, Urine
Reporting Name
Immunoglobulin Total Light Chains,UPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Useful For
Monitoring patients whose urine demonstrates large M-spikes
Confirming the quantitation of specimens that show M-spikes by electrophoresis
Detecting urine monoclonal proteins and identification of specimens that need urine protein electrophoresis
Specimen Type
UrineOrdering Guidance
If serum is being submitted on the same patient for FLCS / Immunoglobulin Free Light Chains, Serum; that test should be ordered under a different order number.
Specimen Required
Submit only 1 of the following specimens:
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Specimen Type: Random urine
Collection Container/Tube: Clean, plastic urine collection container
Submission Container/Tube: Plastic, 5-mL tube
Specimen Volume: 1 mL
Collection Instructions:
1. Collect a random urine specimen.
2. Refrigerate after collection and send refrigerate.
Specimen Type: 24-Hour urine
Container/Tube: Plastic, 5-mL tube
Specimen Volume: 1 mL
Collection Instructions:
1. Collect urine for 24 hours.
2. No additive needed for preservation.
3. Urine may be kept ambient during the collection period but should be refrigerated within 4 hours of collection completion.
Additional Information: See Urine Preservatives-Collection and Transportation for 24-Hour Urine Specimens for multiple collections.
Specimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Urine | Refrigerated (preferred) | 7 days |
| Frozen | 20 days | |
| Ambient | 72 hours |
Day(s) Performed
Monday through Friday
Profile Information
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| KTLCU | Kappa Total Light Chain, U | No | Yes |
| LTLCU | Lambda Total Light Chain, U | No | Yes |
| KLTRU | Kappa/Lambda TLC Ratio, U | No | Yes |
Reference Values
KAPPA TOTAL LIGHT CHAIN
<0.9 mg/dL
LAMBDA TOTAL LIGHT CHAIN
<0.7 mg/dL
KAPPA/LAMBDA RATIO
0.7-6.2
CPT Code Information
83883 x 2
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| TLCU | Immunoglobulin Total Light Chains,U | 44792-0 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| KLTRU | Kappa/Lambda TLC Ratio, U | 33559-6 |
| KTLCU | Kappa Total Light Chain, U | 27365-6 |
| LTLCU | Lambda Total Light Chain, U | 27394-6 |
Test Classification
This test has been modified from the manufacturer's instructions. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.Method Name
KTLCU, LTLCU: Nephelometry