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HelpTest Code PN23 Streptococcus pneumoniae IgG Antibodies, 23 Serotypes, Serum
Reporting Name
S. pneumoniae IgG Ab,23 serotypes,SPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Useful For
Assessing the IgG antibody response to active immunization with nonconjugated, 23-valent pneumococcal vaccines
Assessing the IgG antibody response to active immunization with conjugated 13-valent, 15-valent and 20-valent pneumococcal vaccines
Determining the ability of an individual to produce an antibody response to polysaccharide antigens, as part of the evaluation for humoral or combined immunodeficiencies
Ordering Guidance
This test is the preferred test for patients previously tested for Streptococcus pneumoniae serotypes (as part of follow up testing or part of pre/post vaccine assessment).
The preferred test for patients being evaluated for possible immunodeficiency or for assessment of pneumococcal vaccination response (initial evaluation) is PNTOR / Streptococcus pneumoniae IgG Antibodies, Total, with Reflex, Serum
The preferred test for patients previously tested for total Streptococcus pneumoniae antibodies (as part of follow up testing or part of pre/post vaccine assessment) is PNTO / Streptococcus pneumoniae IgG Antibodies, Total, Serum
Specimen Required
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 0.5 mL
Collection Instructions: Centrifuge and aliquot serum into plastic vial
Specimen Minimum Volume
0.4 mL
Specimen Type
SerumSpecimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 21 days | |
| Frozen | 21 days |
Day(s) Performed
Monday through Friday
Report Available
4 to 6 daysReference Values
Results are reported in mcg/mL
|
Serotype |
Normal value |
|
1 (1) |
≥1.0 |
|
2 (2) |
≥1.0 |
|
3 (3) |
≥1.0 |
|
4 (4) |
≥1.0 |
|
5 (5) |
≥1.0 |
|
8 (8) |
≥1.0 |
|
9N (9) |
≥1.0 |
|
12F (12) |
≥1.0 |
|
14 (14) |
≥1.0 |
|
17F (17) |
≥1.0 |
|
19F (19) |
≥1.0 |
|
20 (20) |
≥1.0 |
|
22F (22) |
≥1.0 |
|
23F (23) |
≥1.0 |
|
6B (26) |
≥1.0 |
|
10A (34) |
≥1.0 |
|
11A (43) |
≥1.0 |
|
7F (51) |
≥1.0 |
|
15B (54) |
≥1.0 |
|
18C (56) |
≥1.0 |
|
19A (57) |
≥1.0 |
|
9V (68) |
≥1.0 |
|
33F (70) |
≥1.0 |
Method Name
Bead-Based Multiplex Immunoassay
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
86317 x 23
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| PN23M | S. pneumoniae IgG Ab,23 serotypes,S | 42366-5 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 620316 | Serotype 1 (1) | 85954-6 |
| 620317 | Serotype 2 (2) | 86039-5 |
| 620318 | Serotype 3 (3) | 86080-9 |
| 620319 | Serotype 4 (4) | 86107-0 |
| 620320 | Serotype 5 (5) | 86130-2 |
| 620321 | Serotype 8 (8) | 86147-6 |
| 620322 | Serotype 9N (9) | 86169-0 |
| 620323 | Serotype 12F (12) | 85977-7 |
| 620324 | Serotype 14 (14) | 85991-8 |
| 620325 | Serotype 17F (17) | 86009-8 |
| 620326 | Serotype 19F (19) | 86024-7 |
| 620327 | Serotype 20 (20) | 86045-2 |
| 620328 | Serotype 22F (22) | 86052-8 |
| 620329 | Serotype 23F (23) | 86064-3 |
| 620330 | Serotype 6B (26) | 27118-9 |
| 620331 | Serotype 10A (34) | 86098-1 |
| 620332 | Serotype 11A (43) | 86122-9 |
| 620333 | Serotype 7F (51) | 25296-5 |
| 620334 | Serotype 15B (54) | 40973-0 |
| 620335 | Serotype 18C (56) | 27395-3 |
| 620336 | Serotype 19A (57) | 40974-8 |
| 620337 | Serotype 9V (68) | 30153-1 |
| 620338 | Serotype 33F (70) | 40969-8 |
| 620404 | Interpretation | 69048-7 |
Forms
If not ordering electronically, complete, print, and send a General Request (T239) with the specimen.