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HelpTest Code PLPMA Prolactin, Pituitary Macroadenoma, Serum
Reporting Name
Prolactin, Pituitary MacroadenomaPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Useful For
Quantifying prolactin in serum specimens where the high-dose hook effect is suspected (eg, presence of pituitary tumor with symptoms of prolactinoma, and lower than expected serum prolactin concentration)
Testing Algorithm
A pituitary adenoma should be identified by imaging studies prior to ordering this test.
Ordering Guidance
For initial patient assessment; order PRL / Prolactin, Serum as the screening test.
Necessary Information
Patient's age and sex are required.
Specimen Required
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 2 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Specimen Minimum Volume
1.75 mL
Specimen Type
SerumSpecimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) | 7 days |
| Frozen | 90 days | |
| Ambient | 24 hours |
Day(s) Performed
Reference Values
Males
<18 years: not established
≥18 years: 4.0-15.2 ng/mL
Females:
<18 years: not established
≥18 years: 4.8-23.3 ng/mL
Method Name
Electrochemiluminescent Immunoassay
Test Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.CPT Code Information
84146
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| PLPMA | Prolactin, Pituitary Macroadenoma | 20568-2 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| PRLR | Prolactin, S | 20568-2 |
| CMT89 | Comment | 48767-8 |
Forms
If not ordering electronically, complete, print, and send an Oncology Test Request (T729) with the specimen.