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HelpTest Code NORT Nortriptyline, Serum
Reporting Name
Nortriptyline, SPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Useful For
Monitoring nortriptyline concentration during therapy
Evaluating potential nortriptyline toxicity
May aid in evaluating patient compliance
Specimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube: Red top (Serum gel/SST are not acceptable)
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions:
1. Collect specimen immediately before next scheduled dose (minimum 12 hours after last dose).
2. Centrifuge and aliquot serum into a plastic vial. Serum must be separated from cells within 2 hours of collection.
Specimen Minimum Volume
0.25 mL
Specimen Type
Serum RedSpecimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum Red | Refrigerated (preferred) | 28 days |
| Frozen | 28 days | |
| Ambient | 7 days |
Day(s) Performed
Monday, Wednesday, Friday
Reference Values
Therapeutic concentration: 70-170 ng/mL
Note: Therapeutic ranges are for specimens collected at trough (ie, immediately before next scheduled dose). Levels may be elevated in non-trough specimens.
Method Name
Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
80299
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| NOTRP | Nortriptyline, S | 3872-9 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 37119 | Nortriptyline, S | 3872-9 |
Report Available
3 to 5 daysForms
If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.