Test Code NICOU Nicotine and Metabolites, Random, Urine
Reporting Name
Nicotine and Metabolites, UPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Useful For
Monitoring tobacco use
Monitoring patients on nicotine-replacement therapy for concurrent use of tobacco products
Specimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Container/Tube: Plastic urine container
Submission Container/Tube: Plastic, 5-mL tube
Specimen Volume: 3 mL
Collection Instructions:
1. Collect a random urine specimen.
2. No preservative.
Specimen Minimum Volume
2 mL
Specimen Type
UrineSpecimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Urine | Refrigerated (preferred) | 28 days |
| Frozen | 365 days | |
| Ambient | 28 days |
Day(s) Performed
Monday through Sunday
Reference Values
Non-tobacco user with no passive exposure:
Nicotine <5.0 ng/mL
Cotinine
<5.0 ng/mL
Anabasine
<2.0 ng/mL
Nornicotine
<2.0 ng/mL
Method Name
Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
G0480
80323 (if appropriate for select payers)
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| NICOU | Nicotine and Metabolites, U | 43125-4 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 82510 | Nicotine | 3854-7 |
| 21321 | Cotinine | 10366-3 |
| 21324 | Nornicotine | 33917-6 |
| 21323 | Anabasine | 33915-0 |
Report Available
2 to 5 daysForms
If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.