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HelpTest Code METHO Methotrexate
Performing Laboratory
Hunterdon Medical Center Laboratory
Useful For
Methotrexate is used in the treatment of certain neoplastic diseases, severe psoriasis, and adult rheumatoid arthritis. Methotrexate has the potential for serious toxicity. Patients undergoing methotrexate therapy are closely monitored to detect toxic effects promptly.
Specimen Requirements
| Container/Tube | Red Top |
| Specimen Volume | 3.0mL |
| Minimum Volume | 1.0mL |
Specimen Type
Serum
Specimen Transport Temperature
Ambient
Specimen Stability
| Temperature | Time Frame |
| Refrigerated 2-8°C | 7 days |
Day(s) Test Set up
Monday through Sunday
Reference Values
< 0.1 umol/L 72 hours after dose.
| Methotrexate Toxicity Indicators: | |
| Level(umol/L) | Post-Dose (Hrs) |
| >10.0 | 24 |
| >1.0 | 48 |
| >0.1 | 72 |
Methodology
Immunoassay
CPT Code
80204
Loinc Code
14836-1