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Test Code GLABP Gliadin (Deamidated) Antibodies Evaluation, IgG and IgA, Serum

Reporting Name

Gliadin (Deamidated) Ab, Eval, S

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Assessment of deaminated gliadin IgA and IgG antibodies for evaluating patients suspected of having celiac disease, including patients with compatible clinical symptoms, patients with atypical symptoms, and individuals at increased risk (family history, previous diagnosis with associated disorder, positivity for HLA DQ2 and/or DQ8)

 

Monitoring response to a gluten-free diet in patients with celiac disease.


Ordering Guidance


Cascade testing is recommended for celiac disease. Cascade testing ensures that testing proceeds in an algorithmic fashion. The following cascades are available; select the appropriate one for your specific patient situation.

-CDCOM / Celiac Disease Comprehensive Cascade, Serum and Whole Blood: complete testing including HLA DQ

-CDSP / Celiac Disease Serology Cascade, Serum: complete serology testing excluding HLA DQ

-CDGF / Celiac Disease Gluten-Free Cascade, Serum and Whole Blood: for patients already adhering to a gluten-free diet

To order individual tests, see Celiac Disease Diagnostic Testing Algorithm.



Specimen Required


Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 0.5 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Specimen Minimum Volume

0.4 mL

Specimen Type

Serum

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 21 days
  Frozen  21 days

Day(s) Performed

Monday, Wednesday, Friday

Reference Values

Negative: <20.0 U

Weak positive: 20.0-30.0 U

Positive: >30.0 U

Reference values apply to all ages.

Profile Information

Test ID Reporting Name Available Separately Always Performed
DAGL Gliadin(Deamidated) Ab, IgA, S Yes Yes
DGGL Gliadin(Deamidated) Ab, IgG, S Yes Yes

Method Name

Enzyme-Linked Immunosorbent Assay (ELISA)

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

86258 x 2

LOINC Code Information

Test ID Test Order Name Order LOINC Value
DGLDN Gliadin (Deamidated) Ab, Eval, S 57776-7

 

Result ID Test Result Name Result LOINC Value
DAGL Gliadin(Deamidated) Ab, IgA, S 47393-4
DGGL Gliadin(Deamidated) Ab, IgG, S 47394-2

Forms

If not ordering electronically, complete, print, and send a Gastroenterology and Hepatology Test Request (T728) with the specimen.

Report Available

2 to 4 days