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HelpTest Code FES Estradiol Free, Serum (includes Estradiol and SHBG)
Reporting Name
Free Estradiol with SHBGPerforming Laboratory
Esoterix EndocrinologySpecimen Required
Collection Container/Tube:
Preferred: Red top
Acceptable: Serum gel tube
Submission Container/tube: Plastic vial
Specimen Volume: 3 mL
Collection Instructions:
1. Within 45 minutes of collection, centrifuge and aliquot 3 mL of serum into a plastic vial.
2. Freeze immediately after separation and send frozen.
Specimen Minimum Volume
1 mL (Note: This volume does not allow for repeat testing.)
Specimen Type
Serum RedSpecimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum Red | Frozen (preferred) | 180 days |
| Ambient | 48 hours | |
| Refrigerated | 48 hours |
Day(s) Performed
Varies
Reference Values
Estradiol, Serum MS
Units: pg/mL
Newborn:
Levels are markedly elevated at birth and fall rapidly during the first week to prepubertal values of <15.
Males <6 m:
Levels increase to 10 - 32 between 30 and 60 days, then decline to prepubertal levels of <15 by six months.
Females <1 y:
Levels increase to 5.0 - 50 between 30 and 60 days, then decline to prepubertal levels of <15 during the first year.
Prepubertal: <15
Adult Males: 8.0 - 35
Adult Females:
Follicular: 30 - 100
Luteal: 70 - 300
Postmenopausal: <15
Free Estradiol, Percent
Units: %
Adult Males: 1.7 - 5.4
Adult Females: 1.6 - 3.6
Free Estradiol, Serum
Units: pg/mL
Adult Males: 0.2 - 1.5
Adult Females: 0.6 - 7.1
Sex Hormone Binding Globulin
Units: nmol/L
Infants (1 - 23m): 60.0 - 252.0
Prepubertal: 72.0 - 220.0
Pubertal:
Males:16.0 - 100.0
Females: 36.0 - 125.0
Adult Males:
20 - 49 y: 16.5 - 55.9
>49y: 19.3 - 76.4
Adult Females:
20 - 49y: 24.6 - 122.0
>49y: 17.3 - 125.0
Method Name
Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS); Equilibrium Dialysis; Immunoradiometric Assay (IRMA)
Test Classification
This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration.CPT Code Information
82681 – Free Estradiol
84270 - Sex Hormone binding globulin
82670 - Estradiol
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| FFES | Free Estradiol with SHBG | Not Provided |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| Z0259 | Estradiol, Serum | 35384-7 |
| Z0228 | Free Estradiol, Percent | 14960-9 |
| Z0229 | Free Estradiol, Serum | 2240-0 |
| Z0230 | Sex Hormone Binding Globulin (SHBG) | 13967-5 |