Test Code ESTR Estriol, Unconjugated, Serum
Reporting Name
Estriol, Unconjugated, SPerforming Laboratory

Useful For
As an adjunct biomarker in the prenatal diagnosis of disorders of fetal steroid metabolism, including Smith-Lemli-Opitz syndrome (1,2) and X-linked ichthyosis (placental sulfatase deficiency disorders)
Evaluating primary or secondary fetal adrenal insufficiency after excluding other rare single gene defects, including aromatase deficiency, 17 alpha-hydroxylase deficiency and/or various forms of congenital adrenal hyperplasia
Specimen Required
Collection Container/Tube:
Preferred: Red top
Acceptable: Serum gel
Submission Container/Tube: Plastic vial
Specimen Volume: 0.6 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Specimen Minimum Volume
0.5 mL
Specimen Type
SerumSpecimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Serum | Refrigerated (preferred) | 14 days | |
Frozen | 90 days |
Day(s) Performed
Monday through Friday
Reference Values
Males: <0.07 ng/mL
Females: <0.08 ng/mL
For International System of Units (SI) conversion for Reference Values, see www.mayocliniclabs.com/order-tests/si-unit-conversion.html.
Test Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.CPT Code Information
82677
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
UE3 | Estriol, Unconjugated, S | 2250-9 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
UE3 | Estriol, Unconjugated, S | 2250-9 |
Method Name
Immunoenzymatic Assay