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Test Code DSG13 Desmoglein 1 (DSG1) and Desmoglein 3 (DSG3), IgG Antibodies, Serum

Reporting Name

Desmoglein 1 and 3, Serum

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Preferred screening test for patients suspected to have an autoimmune blistering disorder of the skin or mucous membranes (pemphigus)

 

Aiding in the diagnosis of pemphigus


Specimen Required


Collection Container/Tube:

Preferred: Red top

Acceptable: Serum gel

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Specimen Minimum Volume

0.5 mL

Specimen Type

Serum

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 14 days
  Frozen  30 days
  Ambient  14 days

Day(s) Performed

Varies

Reference Values

DESMOGLEIN 1:

<20 RU/mL (negative)

≥20 RU/mL (positive)

 

DESMOGLEIN 3:

<20 RU/mL (negative)

≥20 RU/mL (positive)

Method Name

Enzyme-Linked Immunosorbent Assay (ELISA)

Test Classification

This test has been modified from the manufacturer's instructions. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

83516 x 2

LOINC Code Information

Test ID Test Order Name Order LOINC Value
DSGAB Desmoglein 1 and 3, Serum 94335-7

 

Result ID Test Result Name Result LOINC Value
606818 DSG 1 94336-5
606819 DSG 3 94337-3

Report Available

1 to 10 days