Sign in →

Test Code DIMER D-Dimer Exclusion II Assay

Important Note

Note: Deliver within 3 hours.

Performing Laboratory

Hunterdon Medical Center Laboratory

Useful For

The D-Dimer Exclusion II Assay is indicated for use as an aid in the diagnosis of deep venous thrombosis (DVT) and pulmonary embolism (PE) disease.

 

The test is indicated for use in conjunction with a clinical pretest probability assessment model to exclude DVT and PE disease in outpatients suspected of DVT or PE.

 

D-Dimer is not specific for DVT/PE and elevated levels are also observed in a variety of conditions where activation of coagulation and fibrinolysis occurs: e.g. surgery, trauma, infection, inflammation, pregnancy, cancer. This makes D-dimer less useful for exclusion of DVT or PE in hospitalized patients due to the high proportion of comorbid conditions associated with elevated D-dimer levels.

 

Measurement of D-dimer can also be of use as an aid in diagnosing disseminated intravascular coagulation (DIC).

Special Instructions

Note: Specimen must be filled to ETCHED line located on the Blue top tube in order to acheive a ratio of 9 parts blood to 1 part anticoagulant.

Specimen Required

Container/Tube: Blue Top (Na Citrate)

Specimen Volume: Must be filled to ETCHED line located on tube to achieve the proper ratio of 9 parts blood to 1 part anticoagulant.

Specimen Type

Citrated Plasma

Specimen Transport Temperature

Ambient temperature.

Specimen Stability

Ambient temperature. Deliver ≤4 hours.  

Reject Specimen Due To

Tube filled improperly, underfilled or overfilled.

Clotted

Hemolysis

Day(s) Test Set up

Monday through Sunday

Available STAT

Reference Values

Reference values for D-Dimer are age dependent.  Results that fall within the reference range have a negative predictive value for PE/DVT. Results above the upper limit of normal are considered critical.

When there is low or moderate pretest PE/DVT probability, a normal D-dimer has a negative predictive value of approximately 90% for the exclusion of acute pulmonary embolism (PE) or deep vein thrombosis (DVT).

 

Age (Yrs) Upper Limit of Normal  Units: ng{FEU}/mL
0-51 499
52-56 549
57-61 599
62-66 649
67-71 699
72-76 749
77-81 799
82-86 849
Over 86 899

 

 

  

Methodology

Enzyme Linked Fluorescent Assay (ELFA)

CPT Code

85379

Loinc Code

48065-7