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Test Code DEXA Dexamethasone, Serum

Reporting Name

Dexamethasone, S

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Confirming the presence of dexamethasone in serum

 

Confirming the cause of secondary adrenal insufficiency

 

This test is not useful as the sole basis for a diagnosis or treatment decisions.


Ordering Guidance


To detect the metabolite of fluticasone or Flonase, order 17BFP / Fluticasone 17-Beta-Carboxylic Acid, Random, Urine.

 

For synthetic glucocorticoid analyte screen, order SGSS / Synthetic Glucocorticoid Screen, Serum.



Specimen Required


Collection Container/Tube:

Preferred: Red top

Acceptable: Serum gel

Submission Container/Tube: Plastic vial

Specimen Volume: 2 mL

Collection Instructions:

1. Draw blood between 7:30 a.m. and 9:00 a.m. the morning following an evening dose.

2. Centrifuge and aliquot serum into plastic vial within one hour of collection and freeze immediately.


Specimen Minimum Volume

0.6 mL

Specimen Type

Serum

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Frozen (preferred) 28 days
  Refrigerated  7 days
  Ambient  72 hours

Day(s) Performed

Tuesday, Thursday

Report Available

2 to 6 days

Reference Values

Baseline: <30 ng/dL

8:00 a.m. following 1 mg Dexamethasone, previous evening: >100 ng/dL

8:00 a.m. following 8 mg Dexamethasone, (4 x 2 mg doses) previous day: >800 ng/dL

Method Name

Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

80299

LOINC Code Information

Test ID Test Order Name Order LOINC Value
DEXA Dexamethasone, S 14062-4

 

Result ID Test Result Name Result LOINC Value
609439 Dexamethasone, S 14062-4

Forms

If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.