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HelpTest Code DBS1 Diabetes Mellitus Type 1 Evaluation, Serum
Reporting Name
Diabetes Mellitus Type 1 EvaluationPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Useful For
Distinguishing type 1 from type 2 diabetes mellitus
Identifying individuals at risk of type 1 diabetes (including high-risk relatives of patients with diabetes)
Predicting future insulin requirement treatment in patients with adult-onset diabetes
Specimen Required
Collection Container/Tube:
Preferred: Red top
Acceptable: Serum gel
Submission Container/Tube: Plastic vial
Specimen Volume: 4 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Specimen Minimum Volume
2 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 28 days | |
| Frozen | 28 days | ||
| Ambient | 72 hours |
Specimen Type
SerumDay(s) Performed
GAD65 antibody: Monday through Friday
Insulin antibodies: Monday, Wednesday, Friday
IA-2 antibody, Zinc Transporter 8 Antibody: Tuesday, Thursday
Reference Values
GLUTAMIC ACID DECARBOXYLASE (GAD65) ANTIBODY
≤0.02 nmol/L
Reference values apply to all ages.
INSULIN ANTIBODIES
≤0.02 nmol/L
Reference values apply to all ages.
ISLET ANTIGEN 2 (IA-2) ANTIBODY
≤0.02 nmol/L
Reference values apply to all ages.
ZINC TRANSPORTER 8 (ZnT8) ANTIBODY
< 15.0 U/mL
Reference values apply to all ages.
Profile Information
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| DMEI | Diabetes Interpretation, S | No | Yes |
| GD65S | GAD65 Ab Assay, S | Yes | Yes |
| INAB | Insulin Abs, S | Yes | Yes |
| IA2 | IA-2 Ab, S | Yes | Yes |
| EZNT8 | ZnT8 Ab, S | Yes | Yes |
Method Name
GD65S, INAB, IA2: Radioimmunoassay (RIA)
EZNT8: Enzyme-Linked Immunosorbent Assay (ELISA)
DMEI: Interpretive Comments
Test Classification
See Individual Test IDsCPT Code Information
86337
86341 x3
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| DBS1 | Diabetes Mellitus Type 1 Evaluation | 104673-9 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 81596 | GAD65 Ab Assay, S | 30347-9 |
| 89588 | IA-2 Ab, S | 81155-4 |
| 8666 | Insulin Abs, S | 60463-7 |
| 34268 | Diabetes Interpretation, S | 69048-7 |
| 64926 | ZnT8 Ab, S | 76651-9 |